With subjects as diverse as descriptive statistics, study design, statistical inference, and linear and logistic regression, this volume invites the reader to better understand the language of statistics to aid in collaborations with ... Found inside – Page iiThe compilation of articles is complemented by an introduction and comments by Prof. Alfredo Morabia which puts them in the context of current epidemiological research. This hands-on manual also describes over a dozen internationally recognised published guidelines such as CONSORT, STROBE, PRISMA and STARD in a clear and easy to understand format. It is a suitable introduction for anyone without prior knowledge of study design, analysis or conduct as the important concepts are presented throughout the text. Design of Observational Studies is both an introduction to statistical inference in observational studies and a detailed discussion of the principles that guide the design of observational studies. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research. The Oxford Handbook of Research Strategies for Clinical Psychology has recruited some of the field's foremost experts to explicate the essential research strategies currently used across the modern clinical psychology landscape that ... Found insideThe text features an accessible three-part organization that traces the evolution of clinical research and explains the bedrock principles and unique challenges of clinical experimentation and observational research. This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. That is why this book is so timely and important. A unique, in-depth discussion of the uses and conduct of cost-effectiveness analyses (CEAs) as decision-making aids in the health and medical fields, this volume is the product of over two years of comprehensive research and deliberation by ... A report on recommended clinical preventive services that should be provided to patients in the course of routine clinical care, including screening for vascular, neoplastic and infectious diseases, and metabolic, hematologic, ... Found insidePraise for the Second Edition: "... this is a useful, comprehensive compendium of almost every possible sample size formula. "IEA, International Epidemiological Association, Welcome Trust." Found inside – Page iiiAll nerve blocks (head, neck, back, pelvis and lower extremity) are discussed. Pain: A Review Guide is aimed at trainees in pain medicine all over the world. This book will also be beneficial to all practitioners who practice pain. Found insideThe #1 guide to the principles and clinical applications of evidence-based medicine has just gotten better! There is a gap between what is desired - where medical care is provided solely based on high quality evidence - and the reality - where there is limited capacity to generate timely and practical evidence for drug development and to support ... There are no prerequisites for reading this book. The text is basic and has no statistical formulas. Key take-home messages are listed at the end of each chapter. The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Found insideThis book stresses educational approaches that empower pharmacists with patient care and research competencies. The fundamentals described in this text are based on sound scientific methodology, statistical principles and years of accumulated experience by the three authors. On November 28-29, the National Academies of Sciences, Engineering, and Medicine convened a workshop to investigate the current clinical trials system and explore the potential benefits and challenges of implementing virtual clinical trials ... Found insideOn March 3-4, 2016, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop in Washington, DC, bringing together key stakeholders to discuss opportunities for ... While less restrictive and more generalizable than traditional randomized controlled trials, such trials have specific challenges which are addressed in this book. The hope for this work is to provide researchers with programs suitable for meta-analysis with observational studies and clinical trials. In response to the growing availability of archived and real-time digital health data and the opportunities this data provides for research, as well as the increasing number of studies using prospectively collected clinical data, the ... Found insideThis book provides an overall vision and roadmap for improving how the nation uses scientific evidence to identify the most effective clinical services. This book presents a logical system of critical appraisal, to allow readers to evaluate studies and to carry out their own studies more effectively. This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. Found insideHandbook for Clinical Trials of Imaging and Image-Guided Interventions is the first single-source, multi-disciplinary reference, based on the didactic sessions presented at the annual ‘Clinical Trials Methodology Workshop’ for ... The not-to-be-missed, benchmark volume on the growing area of stud in the PharmD pharmacy curriculum. Found insideAn Approach to Evaluate the Effects of Concomitant Prescribing of Opioids and Benzodiazepines on Veteran Deaths and Suicides investigates the effects of opioid initiation and tapering strategies in the presence of benzodiazepines in ... This accessible text provides comprehensive course content that meets and exceeds the curriculum standards set by the Accreditation Council for Pharmacy Education (ACPE). Found insideBased on the tremendous interest in the first two volumes of The Vignettes in Patient Safety series, this third volume follows a similar model of case-based learning. Found insideThis concise book is addressed to researchers, clinical investigators, as well as practicing physicians and surgeons who are interested in the fields of clinical research and trials. Found inside – Page 185These clinical trials changed practice and destroyed the case for the benefits of hormone therapy that had been built up through observational studies. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This edition incorporates current research methodology—including molecular and genetic clinical research—and offers an updated syllabus for conducting a clinical research workshop. This new edition of Practical Transfusion Medicine benefits from even more international authorship than the previous two editions and is an invaluable resource for trainee doctors, scientists, technicians and other staff in haematology and ... The book addresses the main concepts of clinical research, basics of biostatistics, advanced topics in applied biostatistics, and practical aspects of clinical research, with emphasis on clinical relevance across all medical specialties. Planning clinical research requires many decisions. The authors of this book explain key decisions with examples showing what works and what does not. The book is aimed at: Those wishing to learn about clinical trials for the first time, or as a quick reference guide, for example as part of a taught course on clinical trials Health professionals who wish to conduct their own trials, or ... Found inside – Page iThe book provides guidance to the FDA on how it should factor in different kinds of evidence in its regulatory decisions. The contributors to this study present a balanced view of the strengths and weaknesses of randomised controlled trials in the medical setting. They cover all the essential issues without using statistics. This practical guide speaks to two audiences: those who read and those who conduct research. Now available in paperback, the book provides a comprehensive introduction to the subject suitable for graduate students of biostatistics and survival analysis. 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